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Document Type

Poster

Description

Worldwide migraines affect millions of people everyday causing significant impact on their lives. • Often times, patients have failed several first-line therapies for migraine prophylaxis. • The purpose of this systematic literature review is to evaluate the effectiveness and tolerability of TENS devices vs. CGRP antagonists in the application of migraine prophylaxis. • PubMed and ClinicalKey were searched with key terms, 17 sources were selected that were published after 2016. • Sources included meta-analysis, literature review, and randomized control trials. • Data shows that TENS devices as well as CGRP antagonists were effective and safe therapy options for migraine prophylaxis. • More longitudinal research needs to be conducted to further evaluate the efficacy and safety profile of longterm use of these therapy options.

Department

Physician Assistant Studies

Degree Name

Master of Physician Assistant Studies (MPAS)

First Advisor

Andvik, Vicki

Publication Date

Spring 2023

Keywords

Migraine, Migraine prophylaxis, Neuromodulation, TENS devices. CGRP Antagonists

Disciplines

Medicine and Health Sciences

Efficacy of Transcutaneous Electrical Nerve Stimulation vs. Calcitonin Gene Related Peptide Antagonists in the Application of Migraine Prophylaxis

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