Date of Award

Spring 2023

Document Type

Scholarly Project

Degree Name

Master of Physician Assistant Studies (MPAS)

Department

Physician Assistant Studies

First Advisor

Solberg, Julie

Second Advisor

Kauffman, Russell

Keywords

stress urinary incontinence, injection therapy, bulking agents, midurethral sling, surgical sling

Abstract

This literature review aims to assess the comparative efficacy and safety of urethral bulking injection therapy and surgical midurethral sling intervention in the treatment of stress incontinence in women. A comprehensive search of the existing literature was conducted and includes studies from PubMed, an electronic search databases. The findings indicate that both urethral bulking injection therapy and surgical midurethral sling intervention are suitable interventions to be considered for the treatment of stress incontinence in women. Current research available regarding the efficacy of urethral bulking agents versus midurethral slings suggests that the placement of a miduerthral sling has the highest incidence of cure rates and symptom improvement. However, when evaluating the safety of these procedures, the literature suggests that urethral bulking agents offer a superior safety profile when compared with midurethral slings. Future studies with larger sample sizes, universal screening tools, and longer study durations would provide additional, reliable information regarding the long-term efficacy of these interventions and would aide in the decision-making process. The review concludes that both urethral bulking injection therapy and surgical midurethral sling intervention are effective in the treatment of stress incontinence in women, and the choice of treatment should be based on individual patient factors.

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