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Document Type

Poster

Description

Migraines are debilitating and a frequent reason for primary care visits. Migraines interfere with an individual’s work, school, and daily life. Standard of care treatment options for migraine prophylaxis include Propranolol, Amitriptyline, and Topiramate which were all developed for other medical conditions. These conventional medications can lead to unwanted side effects decreasing treatment adherence. Calcitonin Gene-Related Peptide monoclonal antibodies (CGRP mAbs) have been under study for the treatment and prevention of migraines. The purpose of this research project is to explore the effectiveness and tolerability of CGRP mAbs in reducing the number of migraine days in comparison to conventional migraine prophylactic use for individuals who suffer from episodic migraines.

Department

Physician Assistant Studies

Degree Name

Master of Physician Assistant Studies (MPAS)

First Advisor

Kauffman, Russell

Publication Date

Spring 2023

Keywords

Keywords: migraine prevention, episodic migraines, CGRP mAbs, Propranolol, Amitriptyline, Topiramate, Eptinezumab, Galcanzumab, Fremanezumab, Erenumab

Disciplines

Medicine and Health Sciences

A Comparison of Anti-Calcitonin Gene-Related Peptide Monoclonal Antibodies and Standard Migraine Prophylaxis in Those with Episodic Migraines

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