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 The primary aim of this review is to determine the safety and efficacy of left gastric artery embolization (LGAE) in comparison to Roux-en-Y gastric bypass (RYGB) in bariatric patients for the treatment of obesity.  RYGB, an invasive surgical operation, has been proven to result in long-term efficacy of weight loss but can be associated with a higher risk of early and long-term complications to include a gastrojejunal anastomosis leak, surgical site infection, iron deficiency anemia, bowel obstructions, and hernias. RYGB may require reoperation and does have a risk of mortality. Bariatric surgery is now focusing on the appetite-stimulating hormone, ghrelin, which may play a bigger role in reducing weight.  LGAE is a safe, minimally invasive procedure and the evidence has shown promising results in suppression of ghrelin levels leading to significant weight reduction within one year. Adverse events of LGAE include epigastric discomfort, nausea, vomiting, and superficial gastric ulcers. In the studies selected, no deaths were observed following LGAE.  In conclusion, LGAE is a safer option and has proven short-term efficacy in weight loss. However, data is lacking regarding long-term efficacy of LGAE therefore RYGB is still the primary procedural intervention for bariatric patients. Future studies regarding LGAE will need to focus on proper procedural technique to maximize long-term efficacy.  PubMed, Clinical Key, and were utilized to conduct this literature review. All studies selected have a publication date of <10 years.


Physician Assistant Studies

Degree Name

Master of Physician Assistant Studies (MPAS)

First Advisor

Staveteig, Mindy

Second Advisor

Andvik, Vicki

Publication Date

Spring 2023


Medicine and Health Sciences

Weight Loss for Bariatric Patients: Arterial Embolization versus Gastric Bypass