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Document Type
Poster
Description
Research was performed to discuss the epidemiology and current guidelines of Clostridioides difficile infection (CDI), recurrent C. difficile infection (rCDI), the different modalities of fecal microbiota transplantation (FMT), the donor screening process, as well as the safety and efficacy of treatment.
• Utilizing Clinical Key, NCBI database, Dynamed Plus, Cochrane Review, and the websites for the CDC and FDA, a literature review encompassing recent research and human studies relating to CDI.
• Recent studies within five years were preferred, however since C. difficile has sparsely changed, older data was utilized with updates applied accordingly.
• Oral antibiotics are intended for initial infection with C. difficile; while FMT has been shown to reduce recurrence after multiple infections.
• Similar results exist with efficacy and safety for FMT in regards to oral, fresh versus frozen stool, or rectal administration of therapy. With proper screening, FMT is relatively safe and efficacious.
• The need for long-term studies on the safety of FMT has been established and are underway
Department
Physician Assistant Studies
Date of Work
2020
Publication Date
2020
Keywords
Clostridioides difficile infection (CDI), recurrent C. difficile infection (rCDI), fecal microbiota transplantation (FMT), hospital-acquired infection
Disciplines
Medicine and Health Sciences
Recommended Citation
Green, Brenton, "Treatment of Clostridioides Difficile with Fecal Microbiota Transplantation" (2020). Physician Assistant Scholarly Project Posters. 183.
https://commons.und.edu/pas-grad-posters/183