Date of Award
Master of Physician Assistant Studies (MPAS)
Physician Assistant Studies
Abstract Introduction: Preeclampsia during pregnancy warrants therapy with low dose aspirin. The purpose of this review is to investigate whether these women are at increased future risk for cardiovascular morbidity and mortality, and if aspirin therapy should be continued following the puerperium to prevent future cardiovascular events. Research Questions: Do women who had preeclampsia during pregnancy, have increased future cardiovascular morbidity and mortality? Does continued aspirin use in postpartum women, who had preeclampsia during pregnancy, decrease future cardiovascular morbidity and mortality outcomes? Research Methods: Literature review was conducted utilizing CINAHL, Dynamed plus and PubMed databases. Discussion: It is found that further research is necessary to adequately assess if this demographic is at risk. Many studies have found that preeclampsia does increase risk of cardiovascular morbidity and mortality, but that this difference is not statistically significant until later decades in life. There is also new evidence that the risks of bleeding from prophylactic aspirin therapy outweigh the benefit of decreasing cardiovascular and ischemic events. Based on this information, it is prudent to further research and study this group and stratify their risk as well as researching if there is a better modality upon which to provide prophylaxis with lower risk than benefit.
Bohlig, Kristi, "Aspirin use following preeclampsia to prevent future cardiovascular outcomes" (2019). Physician Assistant Scholarly Project Papers. 51.