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Theses/Dissertations from 2024

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Impact Of Endolysosome Iron On Reactive Species Interactome In In-Vitro Models Of HIV-1 Associated Neurocognitive Disorders, Nirmal Kumar

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Maturational Changes In The Epigenome And Transcriptome Of Hypothalamic Astrocytes: Implications For Axonal Regeneration, Abiodun Ebenezer Odufuwa

Theses/Dissertations from 2023

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Understanding NANOG's Role During Cell Differentiation, Oluwatobiloba Samuel Aminu

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The Interplay Between PARP-1 And Histone Modifications In Transcriptional Regulation During Development And Heat Shock Response, Gbolahan Gbenga Bamgbose

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CCl2 Suppression In Lewis Lung Carcinoma Model Enhances Host Survival And Immune Response In The Tumor Microenvironment, Nivedita Biswas

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Neuromodulatory Mechanisms Of Neuropeptides In The Amygdala, Cody Adam Boyle

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The Effect Of Sterol Carrier Protein 2 Gene Ablation And Dietary Cholesterol On Brain And Liver Lipid Composition In Male And Female Mice, Madison Jochim

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Staphylococcal Enterotoxin I Immunotherapy Combined With HLA-DQ8 Induces Tumoricidal Activity, With Low Superantigen Toxicity, Leading To Long-Term Survival And Tumor-Specific Memory Against Established B16-F10 Melanoma In Humanized HLA-DQ8 Transgenic Mice, Nathan Velaris

Theses/Dissertations from 2022

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Role Of Aurora Kinase A, Rab4a, And Endolysosomes In The Development Of Alzheimer’s Disease-Like Pathology, Zahra Afghah

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The Discovery And Investigation Of Jig (CG14850): A Previously Uncharacterized Novel Drosophila Melanogaster Protein, Sayem Hoque Bhuiyan

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Modulation Of Monoamine Transporters By Palmitoylation In Human Health And Disease, Christopher Ryan Brown

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Effects Of Small Molecule FAK Activators On Gastrointestinal Mucosal Healing, Sema Oncel

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The Effects Of The Alpha1a Adrenergic Receptor In Modulating Psychiatric Symptoms, Jason Power

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RSV-Induced Actin Modulation: Contributes To Bronchial Wall Thickening; Does Not Induce Emt, And Is CDC42-Assisted, Sattya Narayan Talukdar

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Translocation Of Yops By Yersinia Pestis Into Canine Cell Lines, Betsy Louise Young

Theses/Dissertations from 2021

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Using Machine Learning On Diverse Datasets To Predict Drug-Induced Liver Injury, Temidayo Adeluwa

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Role Of Gravin/AKAP12 Variants In Regulating Endothelial Cell Behavior, Ashrifa Ali

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Role Of Schlafen 12 In Lung Adenocarcinoma And Triple Negative Breast Cancer, Sarmad Al-Marsoummi

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Transcriptomic Analysis Of Young Regenerating Magnocellular Neurons (MCNs) Vs Mature Non- Regenerating MCNs, Malak Alzidaneen

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Effects Of HIV-1 Gp120 On Intracellular Levels Of Iron And Reactive Oxygen Species: Implications For Lysosomal Stress, Koffi L. Lakpa

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The Effect Of Fatty Acid-Binding Protein 1 Gene Ablation On Brain And Liver Lipid Metabolism, Regan Clarice Lawrence

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Endolysosome Involvement In The Protective Effects Of 17ơ-Estradiol Against HIV-1 Protein-Induced Neuronal Injury, Nicole Miller

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Snail As A Dual DNA/RNA Binding Transcription Factor, Smruthi Rudraraju

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Pathological Role Of Interferon (IFN)-Gamma During Influenza Pathogenesis, Taylor Marie Schmit

Theses/Dissertations from 2020

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Molecular Mechanisms Of Transcriptional Responses In Stress-Induced Human Cells, Sayantani Ghosh Dastidar

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Characterizing Palmitoylation On The Sodium Hydrogen Exchanger Isoform 1 (NHE1), Moriah Hovde

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Interferon-γ Medaites Lung Damage Through The Hyper-Activation Of Ccr2+ Inflammatory Monocytes During Influenza Virus Infection, Mitchell Anthony Klomp

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Contribution Of Intestinal Dysfunction To Alzheimer’s Disease Progression, Mona Sohrabi Thompson

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Investigation Of The Neurological Manifestations Of Lyme Disease And The Impact Of Borrelia Burgdorferi On The Epigenetic Landscape Of Astrocytes, Derick Thompson

Theses/Dissertations from 2019

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Interplay Between Environmental Signals And Chromatin Remodeling During The Process Of Epithelial To Mesenchymal Transition (EMT), Atrayee Bhattacharya

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SPARC, A Matricellular Protein, In A Cell Culture Model Of Heavy Metal Cadmium Induced Bladder Urothelial Carcinoma, Emily Rae Biggane

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Alpha1a-Adrenergic Receptor Modulation Of Epileptiform Activity And Seizures, Joseph Patrick Biggane

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Endolysosome Dysfunction And Inter-Organellar Signalling: An 'Iron-Ic' Story, Peter Halcrow

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Inflammation Is A Common Factor Between Central And Peripheral Neurodegeneration, Brett Anthony Mcgregor

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Avian IgY As An Immunotherapy For Flaviviral Infections, Kyle O'donnell

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Effects Of A Confidence-Based, Individualized Remediation Strategy On Student Learning And Final Grades In A Multi-Campus Human Anatomy Curriculum, Ethan Snow

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Characterization Of Dopamine Transporter Amino Terminal Palmitoylation And Neurotoxic Substrate Activity, Daniel Jacob Stanislowski

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Understanding the Molecular and Cellular Functions of Odd-Skipped Related 1 in Outflow Tract Development, Menglan Xiang

Theses/Dissertations from 2018

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The Involvement Of Polyol Pathway In Hypgerglycemia And Cadmium Toxicity In The Establishment Of Diabetic Neprhopathy, Bethany Anne Davis

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Staphylococcal Enterotoxins G And I Elicit Long-Term Anti-Tumor Responses In Humanized HLA-DQ8αβ Transgenic Mice, Peter Knopick

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Amyloid Precursor Protein And Insulin Homeostasis, Joshua Kulas

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Trpc1-Mediated Ca2+ Entry Regulates Metabolism By Modulating Adipose Differentiation, Autophagy, And Adiponectin Secretion, Anne Schaar

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The Effects Of 27-Hydroxycholesterol And Palmitic Acid On Parkinson's Disease-Like Pathology, Jared Schommer

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Isolation And Characterization Of Stem Cell Population In Human Proximal Tubule Cells And The Effect Of Cadmium In The Isolated Proximal Tubule Stem/progenitor Cell Line., Swojani Shrestha

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Characterization Of Infectious Isolates Of Borrelia Burgdorferi In North Dakota, Bb0399 And Bbb28 In B. Burgdorferi, And Borrelia Miyamotoi In Vitro And In Vivo, Brandee Lynn Stone

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The Role Of The Cholesterol Metabolite, 27-Hydroxycholesterol, In Colon Cancer Cells, Jessica A. Warns

Theses/Dissertations from 2017

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Characterization Of The Immune Stimulating Properties Of Type III Secretion System Needle Protein Bscf From Bordetella Pertussis: Towards The Development Of A New Acellular Pertussis Vaccine, Travis Douglas Alvine

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Acetate Supplementation Reduces Disease Progression, Alters Cns And Myelin Lipid Content, And Influences Cns And Myelin Protein Content In Mice Subjected To Experimental Autoimmune Encephalomyelitis, Amber C. Chevalier

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Mechanisms Of Dopaminergic, Histaminergic, And Glutamatergic Neuromodulation Within The Medial Entorhinal Cortex, Nicholas Ian Cilz

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Mechanistic Insights Into Neutrophil Turnover During Gram-Negative Pneumonic Sepsis, Christopher Jondle

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Amphetamine Exposure During Embryogenesis Leads To Long-Term And Transgenerational Increase In Behavioral Response And Decrease In Dopamine Uptake, Talus J. Mccowan

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Immune Regulatory Mechanism And Myeloid Cells Functions In Brain Parasite Infection, Fredice Quenum Zangbede

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Molecular Mechanisms Regulating Rna Polymerase Ii Pausing During Gene Activation, Ann Sanoji Samarakkody

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The Role Of Α-Synuclein In Brain Lipid Metabolism And Inflammation, Drew R. Seeger

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Epigenetic Remodeling As A Mediator Of Environmental Toxicant Exposure In The Brain, Christopher David Walden

Theses/Dissertations from 2016

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Chronic Amphetamine Exposure Causes Long Term Effects On Dopamine Uptake In Cultured Cells, Nafisa Ferdous

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Characterization Of Two Surface Proteins From The Lyme Spirochete And Their Roles During Mammalian Infection, Robert Anthony Gaultney

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Using Simian Virus 40 As A Model To Determine The Effects Of Replication And Transcription On Histone Methylation, Les Kallestad

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Understanding Addiction, Depression, And Autism Spectrum Disorder Through Structure-Function Analyses Of The Dopamine And Serotonin Transporters, Danielle Krout

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Gata4 Interacts With Hedgehog Signaling Pathway In Regulating Outflow Tract Development, Jielin Liu

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Role Of The Cholesterol Metabolite 27-Hydroxycholesterol In Breast And Prostate Cancer, Shaneabbas S. Raza

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The Impact Of Anterior Gradient 2 (AGR2) Expression In Models Of Arsenite And Cadmium Induced Breast And Bladder Cancers, Jamie Lynn Van Gieson

Theses/Dissertations from 2015

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The Growth And Metabolic Effects Of Pseudouridine Synthase Gene Deletion On Escherichia Coli Strain Bl21, Lisa Marie Burnette

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Alpha1a Adrenergic Receptor Influences On Adult Neurogenesis, Cell Fate, Mood, Learning, Memory, Lifespan, And Cancer Incidence, Katie Collette

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Understanding The Structure-Function Relationships Between Monoamine Neurotransmitter Transporters And Their Cognate Ions And Ligands, Bruce Felts

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Corticotropin-Releasing Factor Facilitates Epileptiform–activity In The Entorhinal Cortex Via CRF2 Signaling Mechanisms, Lalitha Kurada

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Regulation Of Vectorial Active Transport In Human Proximal Tubule Cells By MT-3: The Role Of The C-Terminal Domain On E-And N-Cadherin Expression And The Confirmation Of Protein-Protein Interactions, Andrea Marie Nore

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The N-Terminus Of Type III Secretion Needle Protein YscF From Yersinia Pestis Functions To Modulate Innate Immune Responses, Patrick Osei-Owusu

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Characterization Of Dopamine Transporter Palmitoylation, Danielle Elizabeth Rastedt

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N-Cadherin Expression And EMT Progression In Arsenic- And Cadmium-Transformed Urotsa, Elizabeth Sandquist

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Innate Immune Response To Yersinia Pestis, Sanghita Sarkar

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Dopamine Transporter Phosphorylation, Palmitoylation And Membrane Localization And Mobility In Health And Disease, Madhur Shetty

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Role Of Lectins Receptors In Development Of Sepsis During Pulmonary Bacterial Infection, Anthony Lee Steichen

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The Unique N- And C-Terminal Domains Of Metallothionein-3 Influence The Growth And Differentiation Of Breast Cancer Cells, Brent Jeffrey Voels

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The Role Of Atg7 In The Host Defense Against Bacterial Infection, Yan Ye

Theses/Dissertations from 2014

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The Interplay Between Aging, Growth Hormone, The Methionine Pathway, And Epigenetic Methylation Marks And Mechanisms, Vanessa Louise Armstrong

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Regulation Of Proline-Directed Phosphorylation Site, Threonine 53 On Dopamine Transporter, Sathyavathi Challasivakanaka

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Role Of BipA As A Modulator Of Gene Expression And Ribosome Assembly In Escherichia Coli, Promisree Choudhury

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Attachment Sites Of Irreversible Cocaine Analogs On The Dopamine Transporter, Rejwi Acharya Dahal

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Goose-Derived Igy: A Potential Therapeutic Antibody For The Treatment Of Infectious Disease, Ashley Louisa Fink

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Role Of The α1A-Adrenergic Receptor In Synaptic Plasticity, Cognition & Neurogenesis, Brianna Lynn Goldenstein

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Therapeutic IgY: Safe, Diverse, And Effective For Use Against Viral Targets, Nicole Noel Haese

Theses/Dissertations from 2013

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Acetate Increases Brain Purine Metabolism And Glial Cell Culture Fatty Acid Content: Studies Investigating Glyceryl Triacetate's Therapeutic Mechanism Of Action, Dhaval Paresh Bhatt

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Epigenetic Patterns: Process-Driven Or Sequence-Driven?, Amanda Gefroh

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Inhibition Of The Ysc Type III Secretion System Of Yersinia Pestis By Compound D And Interaction Of Type III Secretion System Needle Proteins With Host Receptors, Danielle L. Jessen

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A Mass Spectrometry-Based Method For Quantification Of Human Metallothionein Isoforms And Usefulness In Biomarker Detection Of Cancers And Metal Toxicity, Aaron Andrew Mehus

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Role Of The Alzheimer's Amyloid Precursor Protein In High Fat Diet Induced Obesity And Regulating Macrophage Phenotype, Kendra L. Puig

Theses/Dissertations from 2012

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Ciliary neurotrophic factor signaling in the magnocellular neurosecretory system : mechanisms of neuronal survival and sprouting, Jason Michael Askvig

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Analysis Of The Role Of Amphetamine In The Induction Of Changes In Histone Modifications Of Dopaminergic Pathway Genes, Amritendu Chakraborty

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Cholesterol Dyshomeostasis And Age Related Macular Degeneration, Bhanu Chandar Dasari

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The Role Of Endolysosomes In Models Of Neurodegenerative Disorders And In Regulating Levels Of Intracellular Calcium, Liang Hui

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Analysis Of Yscf And Associated Homologs And The Presence Of An Inflammatory Molecular Pattern, William Andrew Roughead

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Neuroglial Mechanisms Involved In The Anti-Inflammatory Effect Of Acetate Supplementation, Mahmoud Lotfy Soliman

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Induced Gene Expression In Bladder Cancer: Kindlin-2 And Metallothionein-1x, Sherine Talaat

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Roles of CCAAT/enhancer-binding protein [beta] and [-delta] in immunoglobulin G immune complex-induced Inflammation, Chunguang Yan

Theses/Dissertations from 1994

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The Effect of an Anaerobic Training Program Utilizing A Skating Treadmill on Anaerobic Performance, Lactate, and Other Metabolic Parameters, Trini T. Vargas

Theses/Dissertations from 1991

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Measurement of Ascorbic Acid and Dehydroascorbic Acid in Mammalian Tissues using HPLC with Electrochemical Detection, Debra A. Fry

Theses/Dissertations from 1988

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Lysosomal Enzymes in Undifferentiated and Differentiated HL-60 Cells, Julie J. Ackerman

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A Study of the Effects of Polyethylene Glycol on Interactions Between Glycolytic Enzymes and F-Actin, and Among Glycolytic Enzymes, Julie L. Walsh

Theses/Dissertations from 1985

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Surface Coat Material Associated with the Developing Otic Vesicle, Allan R. Sinning