Kelly Leiphon

Date of Award


Document Type

Independent Study

Degree Name

Master of Science (MS)


Osteoporosis is a serious disease affecting millions in the United States, and postmenopausal women are at great risk for developing osteoporosis. Osteoporosis is characterized by low bone mineral density (BMD) that decreases bone strength and increases risk for fracture. Fractures greatly increase morbidity and mortality in these women, making treatment choices imperative. Bisphosphonates have proven effectiveness in treating osteoporosis, but vitamin D supplementation may also be beneficial as it is vital in the utilization of calcium for bone strength. The purpose of this independent project was to identify the evidence base for best practice in the use of vitamin D and bisphosphonates for the treatment of osteoporosis in postmenopausal women. A comprehensive review of the literature was completed to detennine whether vitamin D supplementation in addition to bisphosphonate use improves BMD, which is a major predictor of bone fragility and risk of fracture. With the evidence obtained from the literature review, best practices regarding vitamin D supplementation in the treatment of postmenopausal women with osteoporosis were determined. This infonnation was presented to primary care providers who care for postmenopausal women who have osteoporosis, or who are at risk for developing osteoporosis