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• Obstructive sleep apnea (OSA) is a disorder that results in loud snoring, gasping respirations, and excessive daytime sleepiness.

• OSA also has the potential to progress to other significant diseases such as hypertension, diabetes mellitus, stroke, and pulmonary hypertension.

• Continuous positive airway pressure (CPAP) has been the first line treatment for OSA since the early 1980’s. Unfortunately, despite the ability of CPAP to significantly improve symptoms of OSA, a large amount of patients struggle to comply with this treatment.

• A new alternative treatment for OSA is hypoglossal nerve stimulation therapy (HGNS), resulting in an increase in muscle tone to the oropharynx, keeping the airway patent during inspiration.

• This review of the literature will examine the efficacy and compliance rates of CPAP, as well as the safety and efficacy of HGNS.

• Research found that there is in fact a need for an alternative therapy for OSA due to high CPAP noncompliance rates.

• The findings also indicate that despite favorable outcomes in clinical trials, more research is needed to determine the prolonged safety and efficacy of HGNS surgery.


Physician Assistant Studies

Degree Name

Master of Physician Assistant Studies (MPAS)

First Advisor

Jay Metzger

Publication Date



Electric Stimulation Therapy; Sleep Apnea, Ostructive -- therapy


Sleep Medicine

Hypoglossal Nerve Stimulation Therapy in Obstructive Sleep Apnea