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• Peripheral neuropathy (PN) is a major public health concern.
• There are many etiologies for PN including injury, infection, toxicity, genetics, metabolic disease and nutritional deficiencies.
• Alpha lipoic acid (ALA), also known as thioctic acid, is a potent antioxidant and cofactor in many cellular metabolic processes.
• Oxidative damage plays a significant role in the pathogenesis of both diabetic peripheral neuropathy (DPN) and chemotherapy induced peripheral neuropathy (CIPN).
• Because of the antioxidant capability ALA has been studied for its potential benefit in preventing and treating PN
Physician Assistant Studies
Master of Physician Assistant Studies (MPAS)
Peripheral Nervous System Diseases -- therapy; Thioctic Acid -- therapeutic use
Nervous System Diseases
Curcio, Jessica, "Alpha Lipoic Acid: A Potential Therapeutic Option for Painful Peripheral Neuropathies" (2015). Physician Assistant Scholarly Project Posters. 95.