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• Patients with systemic lupus erythematosus (SLE) are prone to hypovitaminosis D because of their photosensitivity.
• Vitamin D has beneficial effects not only on bone metabolism but also on the function of the immune system.
• Vitamin D levels depend on many variables, including sun exposure, age, ethnicity, body mass index, use of medications and supplements.
• Patients with SLE avoid the sun because of photosensitive rashes and potential for disease flare, so adequate oral supplementation is critical.
• In addition, to the traditional known metabolic activities, vitamin D has been shown to modulate the immune system, and its deficiency has been linked to the development of several autoimmune disorders including SLE.
• The purpose of this review was to determine if vitamin D has an immunosuppressive effect and if it can suppress autoimmunity.
• The findings indicated that repletion of vitamin D has benefits beyond bone health for patients with certain autoimmune disorders, such as SLE.
Physician Assistant Studies
Master of Physician Assistant Studies (MPAS)
Autoimmune Diseases -- therapy; Lupus Erythematosus, Systemic -- therapy; Vitamin D -- therapeutic use; Vitamin D Deficiency -- complications
Rangen, Pamela, "Vitamin D Supplementation and Systemic Lupus Erythematosus" (2016). Physician Assistant Scholarly Project Posters. 82.