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• Brugada syndrome is a sodium channel deficiency in the myocardium that can cause arrhythmias and sudden cardiac death. The myocardium deficient sodium channels can be inherited or affected by environment factors such as fever or medications.

• Screening for this syndrome can be challenging because many times the first symptom of Brugada syndrome is cardiac arrest. Though incidents of sudden cardiac deaths are low, sudden cardiac death can impact families and communities.

• In Italy, screening ECG’s is claimed to have reduced sudden cardiac events by 85% (Maron, 2014). Preventing sudden cardiac death in these patients through sensible, reasonable preventive practices such as screening electrocardiograms and patient education is the goal.

• Performing 12 lead electrocardiograms (ECGs) in a screening nature and pairing it with medical history and physical exam can help increase discovery of Brugada syndrome and decrease associated cardiac events.

• The American Heart Association and the American College of Cardiology currently do not recommend screening ECGs. The International Olympic Committee and the European Society of Cardiology recommend screening ECGs for athletes.

• The search was limited to articles that were published within the last 10 years. Databases searched included Pubmed, CINAHL, and SPORTDiscus. Several articles were found to be of significance to the topic.


Physician Assistant Studies

Degree Name

Master of Physician Assistant Studies (MPAS)

First Advisor

Jay Metzger

Publication Date



Brugada syndrome -- diagnosis; Death, Sudden, Cardiac -- prevention & control; Electrocardiography; Heart Arrest -- prevention & control; type 1 ECG changes


Cardiovascular Diseases

Brugada Syndrome; Preventive Screening Measures to Decrease Associated
Cardiac Deaths