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• Persistent gastrointestinal (GI) complaints are a common problem in patients presenting to family practice for care.

• Irritable bowel syndrome (IBS) is a diagnosis that adult patients are labeled with when clinicians have exhausted their differential list and no other cause of their GI symptoms can be confirmed.

• Sucrase-isomaltase deficiency (SID) has been historically shown to present early in life as a congenital disorder, but researchers are now recognizing occurrence later in life as a mild or secondary disorder.

• The literature emphasizes the disconcerting prevalence of sucrase-isomaltasedeficiency (SID), the persistent symptoms associated with it, and the need for further research, especially in the adult population.

• SID testing is cost effective, very reliable, and completely non-invasive.

• It has been proven that after treatment of SID with sucrase replacement enzyme, patients were able to return to normal sucrose digestion and had resolution of their symptoms.

• Educating practitioners about SID and providing options for diagnosis and treatment are the first steps in helping the many patients that suffer from chronic bowel problems.


Physician Assistant Studies

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Master of Physician Assistant Studies (MPAS)

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Irritable Bowel Syndrome -- diagnosis; Irritable Bowel Syndrome -- therapy; Sucrase -- deficiency; Sucrase-Isomaltase Complex -- deficiency


Digestive System Diseases | Nutritional and Metabolic Diseases

Sucrase-Isomaltase Deficiency, an Under Considered Diagnosis