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Merriam-Webster defines prolotherapy (PROLO) as “an alternative therapy for treating musculoskeletal pain that involves injection of irritant substance (as dextrose) into a ligament or tendon to promote the growth of new tissue”. Experimental research and multiple clinical trials have generated evidence suggesting that PROLO is effective at treating a variety of musculoskeletal conditions, including tendinopathies, joint instability and ligament laxity. PROLO may also hold a potential to delay or avoid joint replacement and rotator cuff surgeries. Further research is needed to demonstrate the therapeutic effect of PROLO unequivocally.
Physician Assistant Studies
Master of Physician Assistant Studies (MPAS)
Complementary Therapies; Glucose -- therapeutic use; Joint Instability -- drug therapy; Musculoskeletal Diseases -- drug therapy; Tendinopathy -- drug therapy; Tendon Injuries -- drug therapy
Alternative and Complementary Medicine | Musculoskeletal System
Davydov, Boris M., "Prolotherapy: Applications, Mechanism of Action, Controversy and Evidence" (2017). Physician Assistant Scholarly Project Posters. 36.