Efficacy of Prediabetes Management Options for Lowering Cardiovascular Risk
Files
Document Type
Poster
Description
• ≈ 86 million people in the United States are diagnosed with prediabetes: a metabolic syndrome characterized by insulin resistance and inflammation. • Inflammatory nature of the disease increases a patient's cardiovascular risk. • Common treatment options include metformin and lifestyle intervention – primarily exercise and diet plans. However, there is no standard medical recommendation for lowering cardiovascular risk. • Purpose: Determine which treatment options, including the combination of lifestyle and intervention, best lower cardiovascular risk and better detail the effect of prediabetes on cardiovascular risk • Current research provides data showing that prediabetes increases the risk of hypertension and mortality from cardiovascular event. • Reversal from prediabetes to normoglycemia lowered risk of cardiovascular event by almost 50%. • Lifestyle interventions was the best method for lowering cardiovascular risk, while metformin was found to lower the effects of lifestyle intervention when studying the combination of the two. • Future research should determine best course of treatment for patients who aren’t able to complete lifestyle intervention goals such as patients who are bedridden or frail. • Gaining a better understanding of the interaction between metformin and lifestyle intervention will serve invaluable for the future of prediabetes treatment. This research should aid in provider treatment recommendations for prediabetic patients and better detail a “standard” of care.
Department
Physician Assistant Studies
Degree Name
Master of Physician Assistant Studies (MPAS)
Date of Work
2025
Publication Date
Spring 5-2025
Disciplines
Medicine and Health Sciences
Recommended Citation
Mindeman, Cassidy, "Efficacy of Prediabetes Management Options for Lowering Cardiovascular Risk" (2025). Physician Assistant Scholarly Project Posters. 329.
https://commons.und.edu/pas-grad-posters/329