Efficacy of GLP-1 Receptor Agonists in Obese Women with PCOS

Authors

Ellie Fischer, University of North Dakota

Files

Document Type

Poster

Description

• Polycystic ovary syndrome (PCOS) is the most common endocrine disorder in reproductive aged women. • PCOS is characterized by irregular menstrual cycles, hyperandrogenism, and obesity. • This review looked at studies comparing GLP-1 receptor agonists to metformin on PCOS symptoms. • PubMed, Embase, and ScienceDirect were searched from April to July 2024 and ten articles made it past inclusion and exclusion criteria for review in this paper. • In this review, GLP-1 RAs effectively reduce weight and improve glucose metabolism in obese women with PCOS. • GLP-1 RAs in combination with metformin showed even more weight loss and improvement in markers of hyperandrogenism. • Larger studies with standardized treatment approaches and strict lifestyle modification monitoring are needed to confirm these findings.

Department

Physician Assistant Studies

Degree Name

Master of Physician Assistant Studies (MPAS)

Date of Work

2025

Publication Date

Spring 5-2025

Disciplines

Medicine and Health Sciences

Recommended Citation

Fischer, Ellie, "Efficacy of GLP-1 Receptor Agonists in Obese Women with PCOS" (2025). Physician Assistant Scholarly Project Posters. 316.
https://commons.und.edu/pas-grad-posters/316