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The aim of the present review is to evaluate the efficacy and safety of curcumin and fish oil as alternative or adjuvant treatments to NSAIDs and immune modulating medications for the treatment of chronic inflammation.
An online search of CINAHL, PubMed, Cochrane and Alt Healthwatchdatabases was conducted. It was limited to peer-reviewed articles and clinical trials in academic journals within the last ten years.
Current research suggests that curcumin may be efficacious in the treatment of chronic inflammation. It is generally regarded as safe up to 12 gm/day with mild gastrointestinal effects but poor bioavailability has limited its clinical application.
Current research provides evidence that fish oil is efficacious for the treatment of chronic inflammation in a variety of chronic diseases. It is generally regarded as safe at doses of 3 gm/day with mild gastrointestinal effects and no increased risk of bleeding.
In vitro studies have demonstrated a synergistic anti-inflammatory effect when curcumin and fish oil are used concomitantly.
Physician Assistant Studies
Master of Physician Assistant Studies (MPAS)
Curcumin -- adverse effects; Curcumin -- therapeutic use; Fish Oils -- adverse effects; Fish Oils -- therapeutic use; Inflammation -- drug therapy; Comparative Study
Alternative and Complementary Medicine
Andvik, Vicki, "Curcumin and Fish Oil: Potential Alternative or Adjunctive Treatments to NSAIDs and Immune Modulating Medications for the Treatment of Chronic Inflammation" (2017). Physician Assistant Scholarly Project Posters. 31.