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Parkinson disease is multifactorial and predominantly effects the geriatric population. The mainstay of treatment for patients diagnosed is currently symptomatic treatment with dopamine replacement. The goal of this literature review is to identify possible lifestyle modifications that can delay progression of the disease or help prolong OFF time of symptoms. Lifestyle modification predominantly considered during this review included diet and physical activity. Included in the study were MIND, Mediterranean, and DASH diets. Considering the role of medication in this disease levodopa, dopamine agonists, monoamine oxidase B inhibitors and the addition of ropinirole to levodopa and their efficacy in treating parkinsonian symptoms was investigated. A literature review was conducted using electronic search database including, PubMed, Clinical Key and DynaMed. After thorough review of 12 articles regarding management of Parkinson disease with various modifications along with medications it was found lifestyle modifications are not significant in the management of Parkinson disease alone. However, there is evidence to support the benefits lifestyle modifications can have, including diet and physical activity, for those diagnosed with Parkinson disease. The addition of these changes have shown the possibility of reducing the OFF time in the disease as well as reducing the daily medication regimen needed.


Physician Assistant Studies

Degree Name

Master of Physician Assistant Studies (MPAS)

Date of Work


First Advisor

Solberg, Julie

Publication Date

Spring 2024

Lifestyle Changes and Medication vs. Medication Alone: Symptom Control of Parkinson Disease