Download Full Text (487 KB)

Document Type



• This research aimed to review the literature relating to pediatric patients hospitalized with viral bronchiolitis and determine if there is a difference between high-flow nasal cannula (HFNC) and non-invasive ventilation (NIV) in preventing mechanical ventilation, decreasing the length of hospital stay, and decreasing morbidity and mortality.

• A literature review was performed using the electronic search database PubMed. Keyword and mesh terms were used to define a set of literature discussing the use of high-flow nasal cannula versus continuous positive airway pressure in the management of viral bronchitis in pediatric patients. The search revealed a total of 37 studies. All searches were narrowed down to the last five years. Studies that included nebulized, pharmacological treatments were excluded. There were ten studies that met the final criteria.

• The literature suggests that the use of CPAP for initial treatment had better success in not escalating support, but patients on CPAP typically had a longer length of stay. This could have been because if the patient had to be on CPAP, then they had more severe bronchiolitis. There is also the factor of the patient's discomfort with using CPAP. This could cause the need for some sedation to make them more comfortable with the device and also a need for weaning off the sedation. There was no difference in the intubation rate between the two support modes.


Physician Assistant Studies

Degree Name

Master of Physician Assistant Studies (MPAS)

Date of Work


First Advisor

Metzger, Jay

Publication Date

Spring 2024


Medicine and Health Sciences

Viral Bronchiolitis: High Flow Nasal Cannula versus Non-Invasive Ventilation Management’s Effect on Length of Stay, Prevention of Mechanical Ventilation, and Mortality