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•According to the Center for Disease Control (CDC) (2017), the total number of patients diagnosed with diabetes is exceeding 30.2 million and rapidly increasing.

•According to the CDC (2016), approximately 8.5 million people in the United States have peripheral artery disease (PAD), which includes 12-20% of individuals who are older than age 60.

•According to a study performed by Swaminathan et al. (2014), 186,000 patients underwent lower extremity amputation (LEA). Data also shows that patients undergoing LEA have a mortality rate of 20% noted within one year, and a 40% to 50% mortality rate indicated within 18 months.

•The review of literature analyzed studies that compared vascularization procedures to determine whether early diagnosis and intervention provide benefit to reduce lower extremity amputation in diabetic patients with PAD and critical limb ischemia (CLI), and to determine cost effectiveness.

•Research suggests that limb salvage is cost efficient with early detection, proper patient compliance and use of a multidisciplinary approach. However, unpredictable factors such as poor patient compliance may skew cost analyses and validate claims to dispute reduction of costs.


Physician Assistant Studies

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Master of Physician Assistant Studies (MPAS)

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PAD; peripheral arterial disease; limb ischemia; non-traumatic limb ischemia; diabetic neuropathy; diabetic foot ulcers; revascularization procedures; peripheral vascular disease


Cardiovascular Diseases

Limb Salvage for Diabetic Patients with Peripheral Arterial Disease