Comparing Fecal Microbiota Transplant (FMT) to Vancomycin: in Treatment of Recurrent Clostridium difficile Infections (CDI)
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• Clostridium difficile infection (CDI) is the main cause of antibiotic-associated pseudomembranous colitis.
• CDI has tripled over the last ten years due to the increased use of broad spectrum antibiotics. CDI has become increasingly difficult to manage with traditional therapies such as metronidazole and vancomycin due to mutations in the pathogen, resulting in resistant organisms.
• The purpose of this review was to determine if fecal microbiota transplantation (FMT) is more effective in treating and curing CDIs than traditional vancomycin therapy.
• The hypothesis was that FMT will have better treatment outcomes than traditional vancomycin therapy.
• The findings indicated that FMT is a more cost effective, safer, and overall better treatment option for CDI than traditional therapies such as vancomycin.
Physician Assistant Studies
Master of Physician Assistant Studies (MPAS)
Biological Therapy -- methods; Clostridium Infections -- therapy; Fecal Microbiota Transplantation -- methods; Vancomycin -- therapeutic use; Comparative Study
Seil, Christopher, "Comparing Fecal Microbiota Transplant (FMT) to Vancomycin: in Treatment of Recurrent Clostridium difficile Infections (CDI)" (2014). Physician Assistant Scholarly Project Posters. 126.