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• Celiac disease (CD) is a gluten-sensitivity enteropathy that occurs in genetically susceptible individuals upon ingestion of gluten and resolves when gluten is withdrawn from one’s diet.
• Serological markers play a major role in the diagnosis of celiac disease, however a small intestinal biopsy is currently the gold standard in symptomatic individuals.
• The purpose of this study was to determine if serological testing alone is sufficient to confirm the diagnosis of CD and therefore eliminate the need for a biopsy.
• The review of literature explored studies that compared small intestinal biopsy with different serological testing in males and females, <1 to 80 years in age, in order to determine if a biopsy was always necessary.
Physician Assistant Studies
Master of Physician Assistant Studies (MPAS)
Celiac Disease -- diagnosis; Intestine, Small -- pathology; Serologic Tests; Comparative Study
Hanson, Alicia A., "Celiac Disease: Advances in Diagnostic Testing?" (2014). Physician Assistant Scholarly Project Posters. 119.